منابع مشابه
Iodine Alters Gene Expression in the MCF7 Breast Cancer Cell Line: Evidence for an Anti-Estrogen Effect of Iodine
The protective effects of iodine on breast cancer have been postulated from epidemiologic evidence and described in animal models. The molecular mechanisms responsible have not been identified but laboratory evidence suggests that iodine may inhibit cancer promotion through modulation of the estrogen pathway. To elucidate the role of iodine in breast cancer, the effect of Lugol's iodine solutio...
متن کاملIodine nutrition and breast feeding.
A survey of the databanks Medline and Web of science identified studies dealing with maternal and infant iodine nutrition during breast feeding. The iodine concentration of human milk varies widely due to maternal iodine intake. Mean breast milk iodine concentrations are reported as ranging from 5.4 to 2170 microg/L (median 62 microg/L) in worldwide studies. In the few studies that compared len...
متن کاملComparison of estrogens and estrogen metabolites in human breast tissue and urine
BACKGROUND An important aspect of the link between estrogen and breast cancer is whether urinary estrogen levels are representative of the intra-tissue levels of bioavailable estrogens. METHODS This study compares 15 estrogen and estrogen metabolite levels in breast tissue and urine of 9 women with primary breast cancer using a quantitative liquid chromatography-mass spectrometry method. RE...
متن کاملRelationship between Urine and Plasma Estrogen Ratios1
Normal young and postmenopausal women were placed into groups according to the ratio of the estrogens in their urine. Women whose ratio was 1.3 if young and 3.2 if postmenopausal were compared to women whose ratio was 0.7 and 2.1 for young and postmenopausal, re spectively. Between the respective highand low-ratio groups, there were no significant differences for circulat ing levels of estriol,...
متن کاملEstrogen plus progestin and risk of benign proliferative breast disease.
Women with benign proliferative breast disease are at increased risk of subsequent breast cancer. Estrogens and progesterone exert proliferative effects on mammary epithelium, and combined hormone replacement therapy has been associated with increased breast cancer risk. We tested the effect of conjugated equine estrogen plus progestin on the risk of benign proliferative breast disease in the W...
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ژورنال
عنوان ژورنال: Journal of Cancer Therapy
سال: 2012
ISSN: 2151-1934,2151-1942
DOI: 10.4236/jct.2012.36152